There remains a significant unmet need for effective and sustainable treatment for inflammatory disease such as Rheumatoid Arthritis, despite a much greater understanding of the disease mechanism over the past decade. Clinical trial inclusion/exclusion criteria and the higher risk associated with biologics can cause challenges with patient recruitment but O4 Research has successfully avoided many of the common study related issues by applying our knowledge and experience of studies in this therapeutic area.
One of our key objectives with such studies is to really understand the patient pathway and ensure that the study design and protocol is practical for investigative sites to conduct and not unnecessarily prohibitive, whilst still enabling the key study objectives to be achieved. This also prevents the inevitable protocol amendments that often arise in the absence of a holistic and methodical approach being applied at the design stage. Our key expertise in this area include Osteoarthritis, Rheumatoid Arthritis, Osteoporosis and Gout.